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1.
Acta Medica Philippina ; : 68-71, 2021.
Article in English | WPRIM | ID: wpr-959955

ABSTRACT

@#<p style="text-align: justify;"><strong>Objective.</strong> To create an age-based formula to estimate the base curve needed for contact lens fitting using measured central corneal curvature (CCC) with a handheld auto keratometer from ophthalmologically normal infants.</p><p style="text-align: justify;"><strong>Methods.</strong> This is a prospective cross-sectional study involving 70 ophthalmologically normal full-term infants aged 0 to 12 months. The infants were divided into four groups: 0-3 months, >3-6 months, >6-9 months and >9-12 months. CCC was measured with a handheld auto keratometer and was used to compute for the base curve. Differences in CCC between the four groups were measured and linear regression models were used for formula creation.</p><p style="text-align: justify;"><strong>Results.</strong> The mean CCC was highest in group 1 at 45.5 ±2.4 diopters (D). These values slowly decreased as age increased. A formula predictive of the base curve based on the infants age was derived using linear regression analysis. It predicted that for every month increase in age, there is a 0.063 millimeter increase in the base curve (p<0.001).</p><p style="text-align: justify;"><strong>Conclusion.</strong> Infant CCC is highest at birth and gradually decreases as age increases. The formula can predict the base curve needed for contact lens fitting in infants without the need for a handheld autokeratometer.</p>


Subject(s)
Infant , Contact Lenses
2.
Philippine Journal of Ophthalmology ; : 73-77, 2014.
Article in English | WPRIM | ID: wpr-633488

ABSTRACT

@#<p style="text-align: justify;"><strong>OBJECTIVE:</strong> To compare the recurrence rate after conjunctival autograft alone versus conjunctival autograft with mitomycin-C in the treatment of primary and recurrent pterygium.<br /><strong>METHODS:</strong> This was a prospective, randomized, interventional comparative study of patients with primary and recurrent pterygium who were randomized to receive either simple excision with conjunctival autograft (CA) or simple excision with CA and mitomycM-C applied. They were followed up for 6 months and observed for recurrence of the pterygium. Statistical analyses were used to compare the 2 groups.<br /><strong>RESULTS:</strong> Fifty-eight patients (62 eyes) diagnosed with primary and recurrent pterygium were evaluated. The mean age was 44.81 ± 12.35 years (range 25 to 70 years). Thirty eyes were treated with conjunctival autograft (15 primary, 15 recurrent) and 32 eyes (17 primary, 15 recurrent) with conjunctival autograft combined with Mtraoperati-ve application of low-dose raitomycin. -C (0.02% for 3 minutes). The mean follow-up period was 25 ± 1.40 months (range 24 to 28 months). There was a 3.22% recurrence rate (2 eyes) from the recurrent pterygium group. There was no significant difference 11.1  the rate of recurrence (p = 0.53) between the 2 treatments for both primary and recurrent pterygium. No mitomycM C-related complication was observed during the length of the study.<br /><strong>CONCLUSION:</strong> Conjunctival autograft surgery alone for primary and recurrent pterygium is effective and safe in reducing the recurrence rate of pterygium within" 6 months.</p>


Subject(s)
Humans , Male , Female , Aged , Middle Aged , Adult , Pterygium , Mitomycin , Autografts , Conjunctiva , Transplantation, Autologous
3.
Rev. argent. reumatol ; 18(1): 26-29, 2007. ilus
Article in Spanish | LILACS | ID: lil-516767

ABSTRACT

La literatura médica refiere bastamente la asociación de neoplasia y enfermedad reumática pero, en general, de una manera poco consistente. Neoplasmas sólidos, linfomas, mielomas y leucemias pueden causar enfermedad reumática por infiltración o por mecanismos inmunológicos, pero en la mayoría de los casos es difícil demostrar causalidad.1 Numerosos autores debaten este tema, existen muchas publicaciones internacionales al respecto citándose diferentes tipos de cáncer en el contexto de varios síndromes de naturaleza autoinmune. 2,3 Síndromes autoinmunes paraneoplásicos se observan también en pacientes con enfermedad mielodisplásica. Una revisión de casos individuales y pequeñas series sugieren que alrededor del 10% de estos pacientes puede experimentar varios síndromes autoinmunes, incluyendo como manifestaciones clínicas más frecuentes vasculitis cutáneas y sistémicas, fiebre, artritis, infiltrados pulmonares, polineuropatía periférica, enfermedad intestinal inflamatoria y glomerulonefritis que habitualmente responden también al tratamiento inmunosupresor o esteroideo


Subject(s)
Female , Arthritis , Leukemia, Myeloid , Sarcoma, Myeloid
4.
Rev. argent. urol. (1990) ; 64(4): 189-95, oct.-dic. 1999. tab, graf
Article in Spanish | LILACS | ID: lil-258722

ABSTRACT

Objetivo: Establecer la experiencia de un grupo cooperativo sobre tumores renales incidentales y los menores de 5 centímetros. Material y métodos: Se realizó un análisis retrospectivo de los adenocarcinomas renales operados con nefrectomía radical en el período 1986-1996. Se seleccionaron los tumores incidentales, los menores de 5 centímetros, y se realizó un análisis de la función renal posoperatoria de los pacientes. Resultados: Se analizaron 231 tumores renales; 32 por ciento fueron dianóstico incidental (74 pacientes); 35,5 poor cientoi fueron tumores menores de 5 cm (82 pacientes). Se halló que los tumores incidentales se poresentaron en estadios más bajos (62 por ciento Edios 1 y 2), y con mayor porcentaje de tumores menores de 5 cm (51,3 por cientoi) (p=<0,01). La sobrevida de los tumores menores de 5 cm fue estadísticamente superior a los mayores a esa cifra (p=<0,001). Se halló un 7,8 por ciento de detioro de la función renal posoperatoria (3,9 transitoriay 3,9 definitiva), con cifras de creatinina superiores a 1,5 mg/dl. Ningún paciente con tumor incidental o menor de 5 cm requirió hemodiálisis. Conclusiones: Los tumores renalrs incidentales de 5 cm son una entidad cada vez m,ás frecuente, y suelen coincidir con estadios bajos. La nefrectomía radical parece ser una técnica adecuada para su tratamiento, con escaso deterioro de la función renal posoperatoria, y 0 por ciento de necesidad de hemodiálisis


Subject(s)
Humans , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , Kidney Neoplasms/therapy , Nephrectomy , Size Perception/classification
5.
Rev. argent. urol. (1990) ; 64(3): 122-7, jul.-sept. 1999. tab, graf
Article in Spanish | LILACS | ID: lil-248536

ABSTRACT

Objetivo: Establecer factors pronósticos en el adenocarcinoma renal.Material y método: Se realizó un estudio retrospectivo de todos los casos de adenocarcinoma renal operados por los miembros del Club urológico del sur de la provincia de Buenos Aires que participaron en este estudio, entre los años 1986 y 1996. Resultados: Se revisaron 231 casos de carcinoma renal operados en ese período. La edad fue de 62+= 11,63 por ciento fueron hombres. La sobrevida a 5 años fue : 100 por ciento estadio I, 77 por ciento estadio II, 51 por ciento estadio III y, 0 por ciento estadio IV; 32 por ciento fueron incidentales. Los pacientes < de 60 años y los tumores > de 5 cm presentaronmenor sobrevida. Conclusiones: Los tumores de bajo estadio (I y II), < de 5 cm, y en pascientes mayores de 60 años tienen mejor pronóstico en cuanto a la sobrevida global


Subject(s)
Humans , Male , Female , Middle Aged , Adenocarcinoma , Kidney Neoplasms/diagnosis , Kidney Neoplasms/surgery , Prognosis , Kidney/pathology
6.
Rev. argent. urol. (1990) ; 64(2): 107-14, abr.-jun. 1999.
Article in Spanish | LILACS | ID: lil-241906

ABSTRACT

Objetivo: Establecer la incidencia de insuficiencia renal posoperatoria en pacientes nefrectomizados por adenocarcinoma renal. Material y método: Se analizaron retrospectivamente todas las nefrectomías por cancer renal realizadas por los participantes en el estudio entre los años 1986 y 1996. Se evaluó la presencia de insuficiencia renal pre y posoperatoria tomando valores de creatinina de 1,5 mg/dl como límite superior. Se evaluó si hubiera sido posible realizar cirugía conservadora en cada caso. Resultados: se revisaron 231 casos de nefrectomía por cáncer. El 7,8 por ciento presentó insuficiencia reanl posoperatoria (3,9 por ciento transitoria y 3,9 por ciento definitiva) con creatininas>1,5 mg/dl. Sólo el 0,43 por ciento requirió hemodiálisis crónica. La falla renal se presentó a los 18,7 meses posoperatorios. Dentro del grupo donde se hubiera podido efectuar cirugía conservadora, el 2,1 por ciento presentó insuficiencia renal definitiva. Conclusiones: La incidencia de falla renal posnefrectomía es del 7,8 por ciento(3,9 definitiva y 3,9 por ciento transitoria). Sólo el 0,43 por ciento requiere hemodiálisis crónica


Subject(s)
Humans , Male , Aged , Middle Aged , Kidney Neoplasms/surgery , Neoplasms/surgery , Nephrectomy , Renal Insufficiency/surgery , Case-Control Studies
7.
Philippine Journal of Anesthesiology ; : 13-20, 1999.
Article in English | WPRIM | ID: wpr-632085

ABSTRACT

BACKGROUND: Clonidine, an alpha-agonist has been postulated to produce analgesia centrally by stimulating the post-synaptic activity of norepinephrine through receptors distinct from opioid receptors and peripherally through a mechanism similar to local anesthetics. It has been suggested that the use of a combination of local anesthetics and clonidine both at lower doses may be effective in providing adequate analgesia at the same time minimizing the deleterious side effects of each drug when used alone at higher doses. The objective of the study was the determination of the minimum dosage of clonidine in combination with bupivacaine necessary for epidural administration that would provide optimal intraoperative and postoperative analgesia with the least occurrence of side effects such as hypotension and bradycardia. METHODOLOGY: One hundred randomly selected, healthy ASA l and 2 gynecologic patients undergoing lower abdominal surgery under epidural anesthesia were given bupivacaine 0.5 percent epidurally compounded with either saline as placebo (Group 1), or clonidine in variable doses: 0.5 ug/kg (Group 2), 1.0 ug/kg (Group 3), and 1.5 ug/kg (Group 4) in a randomized, double-blind fashion. The vital signs were noted every 5 minutes. Analgesia was monitored and recorded using the Visual Analog Scale (VAS), Verbal Rate Scoring and the systemic indicators of pain perception (SBP 30 min Hg increase from baseline or heart rate 20 percent from baseline). A top-up dose of Lidocaine 2 percent was given with systemic indications of pain perception noted intraoperatively or rescue doses of opioids were given when the systemic indications of pain perception were noted at the post anesthesia care unit, upon which data collection was terminated Eighty two patients completed the course of data collection while eighteen were dropped out because of sacral sparing, retraction pain and extension of incision. The statistical tool utilized to test significant differences between the groups was the Kruskal-Wallis Analysis of Variance test and the Partitioned Chi-square test. RESULTS: There is prolongation in the duration of analgesia with incremental increase in clonidine dose. Hypotension occurred even without the addition of clonidine with higher incidence as the dose of clonidine increased. The least side effects occurred with doses of clonidine between 0.5 and 1.0 ug/kg. CONCLUSION: The optimal dosage of clonidine for intraoperative analgesia that would extend to the postoperative period in Filipino women would fall between 0.5 to 1.0 ug/kg. (Author)


Subject(s)
Humans , Analgesia , Bupivacaine , Clonidine , Analgesia, Epidural
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